WELD COUNTY, Colo. (CBS4) — A woman and a child have died and another child and a man are in critical condition after a crash that shut down Highway 52 in Weld County Friday morning.

The highway was closed at Weld County Road 41, according to the sheriff’s office.

A woman in her 20s, who is believed to have caused the crash, has died, the sheriff’s office confirmed.

Two children in her vehicle were rushed the the hospital by ambulance because the medical helicopter couldn’t fly due to the foggy weather, according to Trooper Gary Cutler.

A 5-year-old boy was taken to Platte Valley Medical Center in Brighton but doctors could not save him, Trooper Cutler said.

A 3-year-old girl was taken to Children’s Hospital and was in critical condition.

A man who was driving the other vehicle involved was ejected from his vehicle, Cutler said. That man is also hospitalized in critical condition.

Two other vehicles were involved, but those occupants were not hurt.

There was heavy fog in the area at the time of the crash but investigators are still working to determine the cause.

The Colorado State Patrol will be in charge of the the investigation.

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