DENVER (CBS4) – Two members of a four-person family died Saturday night when a wrong-way driver collided with their vehicle in the HOV lane on Interstate 25.

(credit: CBS4)

The wreck occurred just before 6 p.m. and affected lanes of I-25 traffic for several hours.

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The Colorado State Patrol said the female driver of a black Jeep survived the crash and was transported to a local hospital. She was driving southbound. The high-occupancy-vehicle lanes were open for northbound traffic at the time.

The Jeep struck a another vehicle carrying a family of four.

(credit: CBS4)

CSP Trooper Gary Cutler said two people from that vehicle passed away. CBS4 has confirmed the fatalities from that vehicle, a tan Honda CRV, are driver Miguel Guiterrez, 47, and a 17-year-old male passenger.

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The driver of the Jeep has also been named: Kimberly Rodriquez Roldan. She is 24 years old.

Cutler also said alcohol is suspected in the crash.

(credit: Colorado Department of Transportation)

Cutler said a third vehicle was involved in the accident, but its occupants are expected to be okay.

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The HOV lanes were re-opened at 2:45 a.m. Sunday, according to the Colorado Department of Transportation.