(CNN) — The US officially relocated its Embassy to Jerusalem on Monday, formally upending decades of American foreign policy in a move that was met with clashes and protests along the Israeli-Gaza border.

At least 43 Palestinians were killed in Gaza as deadly protests took place ahead of and during the ceremony in Jerusalem — making it the deadliest day there since the 2014 Gaza war.

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Palestinians carry an injured protesters after Israel’s intervention during a protest, organized to mark 70th anniversary of Nakba, also known as Day of the Catastrophe in 1948, and against United States’ plans to relocate the U.S. Embassy from Tel Aviv to Jerusalem, near Israeli border in eastern part of Shuja’iyya neighborhood of Gaza City, Gaza on May 14, 2018. (Photo by Ali Jadallah/Anadolu Agency/Getty Images)

President Donald Trump did not attend the ceremony in Jerusalem’s Arnona neighborhood, but in a video message broadcast at the event he congratulated Israel, saying the opening had been “a long time coming.”

“Today, Jerusalem is the seam of Israel’s government. It is the home of the Israeli legislature and the Israeli supreme court and Israel’s prime minister and president. Israel is a sovereign nation with the right like every other sovereign nation to determine its own capital, yet for many years, we failed to acknowledge the obvious, the plain reality that Israel’s capital is Jerusalem,” Trump said in the pre-recorded remarks.

“As I said in December, our greatest hope is for peace,” he added.

Politicians and dignitaries including Ivanka Trump and her husband Jared Kushner watched as US Treasury Secretary Steve Mnuchin unveiled the US seal, turning what was formally the consulate building into the Embassy.

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White House senior adviser Jared Kushner called for unity Monday at the opening of the United States’ new embassy in Jerusalem, according to excerpts of his speech released by the White House. (CNN)

Kushner, who is also a senior adviser to the US President, called for unity in his address.

“We believe, it is possible for both sides to gain more than they give — so that all people can live in peace — safe from danger, free from fear, and able to pursue their dreams,” he said.

“Jerusalem must remain a city that brings people of all faiths together.”

Israeli Prime Minister Benjamin Netanyahu thanked Trump for his support on Twitter hours ahead of the opening ceremony.

“What an amazing day! Thank you, @POTUS Trump,” Netanyahu said while re-tweeting a Twitter post from Trump.

The opening of the Embassy happened a day after Israel celebrated Jerusalem Day, marking what Israelis consider the reunification of the city.

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GAZA CITY, GAZA – MAY 14: Israeli security forces intervene Palestinians during a protest, organized to mark 70th anniversary of Nakba, also known as Day of the Catastrophe in 1948, and against United States’ plans to relocate the U.S. Embassy from Tel Aviv to Jerusalem, at Gaza-Israel border near Jabalia Refugee Camp on May 14, 2018. (Photo by Ramez Habboub/Anadolu Agency/Getty Images)

Speaking at the ceremony, Netanyahu hailed the alliance between America and Israel as “stronger than ever.”

“What a glorious day, remember this moment. This is history,” he said.

“President Trump by recognizing history, you have made history. All of us are deeply moved, all of us are deeply grateful.”

Monday was the 70th anniversary of the founding of the State of Israel (though not according to the Jewish calendar by which it is normally marked in Israel — that was last month).

On Tuesday, Palestinians will mark what they call the “Nakba” or Catastrophe, in memory of the more than 700,000 Palestinians who were either driven from, or fled, their homes during the Arab-Israeli war that accompanied the creation of the State of Israel in 1948.

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A picture taken on May 14, 2018 from the southern Israeli kibbutz of Nahal Oz across the border with the Gaza Strip shows tear gas canisters launched by Israeli forces falling down on Palestinian protesters gathering along the border fence with Israel. (credit: JACK GUEZ/AFP/Getty Images)

Trump’s decision to declare Jerusalem the capital of Israel and relocate the Embassy from Tel Aviv is contentious for Palestinians, who hope to claim part of the city as their future capital.

The city is also home to deeply holy sites for Jews and Christians. The issue has been so thorny that international negotiators had left the question of Jerusalem to the final stages of any peace deal.

(The-CNN-Wire™ & © 2018 Cable News Network, Inc., a Time Warner Company. All rights reserved.)

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