DENVER (CBS4) – Major delays are expected Tuesday night as the Colorado Department of Transportation will realign southbound Interstate 25 near Alameda Avenue onto new concrete pavement.

“There will be multiple lane and ramp closures on southbound I-25 from 8 p.m. until 5:30 a.m. on Wednesday,” Mindy Crane with CDOT said in a statement. “Motorists are encouraged to avoid southbound I-25 and seek alternate routes.”

CDOT also wants to remind motorists to obey all construction signs and flaggers and to “Slow for the Cone Zone” to keep workers safe.

Crane said the work is part of a $37.4 million American Recovery and Reinvestment Act (ARRA) project that will replace the Alameda Avenue bridge over I-25.

For e-mail updates on the project, visit www.coloradodot.info and click on the icon in the upper right corner. The link will take you to a list of items you can subscribe to including the I-25/Alameda Avenue project listed under “Projects.”